Medical Literature - 1972

Hereditary angioneurotic oedema in three families. Symptomatic heterogeneity, complement analysis and therapeutic trials.

Blohme G, Ysander L, Korsan-Bengtsen K, Laurell AB. 3/1972 Acta Medica Scandinavica


Not available online.

Tranexamic acid therapy in hereditary angioneurotic edema

Sheffer AL, Austen KF, Rosen FS. 8/1972 The New England Journal of Medicine

Aug 31;287(9):452-454.

Available online at: (small fee)

Treatment of hereditary angioneurotic oedema with tranexamic acid. A random double-blind cross-over study.

Blohme G. 10/1972 Acta Medica Scandinavica

Acta Med.Scand. 1972 Oct;192(4):293-298.

Five patients with hereditary angioneurotic oedema (HANE) have been treated, in a random double-blind cross-over study, with tranexamic acid (trans-AMCHA). Three patients have reacted positively to the treatment. The positive effect in these cases has been so obvious that a specific effect of trans-AMCHA seems probable even if it cannot be definitely ruled out that spontaneous variations have been the cause of this effect. Therapeutic trials with fibrinolytic inhibitors should be made on patients with HANE.

Available online at: (small fee)

Funding for Canadian Hereditary Angioedema Network has been generously provided by unrestricted grants from:


CSL Behring


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